Salmonella enterica Serotype Typhimurium DT 104 Antibiotic Resistance Genomic Island I in Serotype Paratyphi B
نویسندگان
چکیده
We have identified Salmonella genomic island I (SGI1) in an isolate of Salmonella enterica serotype Paratyphi B. This antibiotic-resistance gene cluster, which confers multidrug resistance, has been previously identified in S. enterica serotype Typhimurium phage types DT 104 and DT 120 and in S. enterica serotype Agona.
منابع مشابه
The genomic island SGI1, containing the multiple antibiotic resistance region of Salmonella enterica serovar Typhimurium DT104 or variants of it, is widely distributed in other S. enterica serovars.
The global dissemination of the multiply-antibiotic-resistant Salmonella enterica serovar Typhimurium DT104 clone with the resistance genes located in a class 1 integron, here designated In104, within genomic island SGI1 is a significant public health issue. Here, we have shown that SGI1 and variants of it carrying different combinations of resistance genes are found in several Salmonella enter...
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Sir, Enteric fever, comprising both typhoid and paratyphoid fevers, continues to be a global health problem with an estimated 12–33 million cases occurring worldwide each year. Paratyphoid fever is caused by Salmonella Paratyphi A, B and C and multidrugresistance (MDR), defined as resistance to the three first-line agents chloramphenicol, ampicillin and co-trimoxazole, is an emerging problem in...
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Salmonella genomic island 1 (SGI1) contains an antibiotic resistance gene cluster and has been previously identified in multidrug-resistant Salmonella enterica serovars Typhimurium DT104, Agona, and Paratyphi B. We identified a variant SGI1 antibiotic-resistance gene cluster in a multidrug-resistant strain of S. enterica serovar Albany isolated from food fish from Thailand and imported to Franc...
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1. Threlfall EJ. Epidemic Salmonella typhimurium DT104 – a truly international epidemic clone. J Antimicrob Chemother. 2000;46:7–10. 2. Lawson AJ, Desai M, O’Brien SJ, Davies RH, Ward LR, Threlfall EJ. Molecular characterisation of an outbreak strain of multiresistant Salmonella enterica serovar Typhimurium DT104 in the UK. Clin Microbiol Infect. 2004;10:143–7. 3. Briggs CE, Fratamico PM. Molec...
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Multiresistant Salmonella enterica serotype Typhimurium definitive phage type (DT) 12 and DT 120 are more closely related to DT 104 than to non-multiresistant strains of their respective phage types. Multiresistant DT 12 and DT 120 appear to have arisen due to changes in phage susceptibility of DT 104 rather than horizontal transfer of resistance genes.
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